Mice have discovered a single hormone that can help them live longer.
The hormone in question is fibroblast growth factor 21 (FGF21), which is produced by the liver.
FGF21 responds to protein restriction in male mice, boosting energy expenditure and glucose tolerance while reducing body weight, according to current research.
"FGF21-deficient mice are not only resistant to the health [benefits] of [protein restriction], but they also show early-onset weight loss, greater frailty,
The latest findings imply that protein restriction's pro-longevity effects are mediated by a single hormone found in humans.
Although it is uncertain whether FGF21 has the same role in people as it does in mice, studies on humans reveal that low-protein, high-carbohydrate diets may have similar metabolic benefits.
The circulating FGF21 is likewise affected by these macronutrients.
Mice studies are assisting scientists in better understanding the role of this hormone in the body.